跳至內容

乙酰克里定

維基百科,自由的百科全書
乙酰克里定
Skeletal formula of aceclidine
Ball-and-stick model of the aceclidine molecule
臨床資料
AHFS/Drugs.com國際藥品名稱
給藥途徑Topical (ophthalmic solution)
ATC碼
法律規範狀態
法律規範
  • 處方藥(-only)
藥物動力學數據
藥物代謝deacetylation?
識別資訊
  • 1-Azabicyclo[2.2.2]oct-3-yl acetate; 3-Quinuclidinyl Acetate
CAS號827-61-2  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.011.431 編輯維基數據鏈接
化學資訊
化學式C9H15NO2
摩爾質量169.22 g·mol−1
3D模型(JSmol英語JSmol
  • O=C(OC2C1CCN(CC1)C2)C
  • InChI=1S/C9H15NO2/c1-7(11)12-9-6-10-4-2-8(9)3-5-10/h8-9H,2-6H2,1H3 checkY
  • Key:WRJPSSPFHGNBMG-UHFFFAOYSA-N checkY

乙酰克里定醋克利定是一種有機化合物,化學式為C9H15NO2。它可由3-喹核醇德語3-Chinuclidinol乙酸酐反應製得。[1]它和3-溴溴苄反應,得到季銨鹽N-(3-溴苄基)乙酰克里定溴化物。[2]

參考文獻

[編輯]
  1. ^ M. H. Shaw, V. W. Shurtleff, J. A. Terrett, J. D. Cuthbertson, D. W. C. MacMillan. Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles. Science. 2016-06-10, 352 (6291): 1304–1308 [2021-08-15]. ISSN 0036-8075. PMC 5114852可免費查閱. PMID 27127237. doi:10.1126/science.aaf6635 (英語). 
  2. ^ Primozic, Ines; Bolant, Marijana; Ramic, Alma; Tomic, Srdanka. Preparation of novel meta and para substituted N-benzyl protected quinuclidine esters and their resolution with butyrylcholinesterase. International Electronic Conference on Synthetic Organic Chemistry, 15th, Nov. 1-30, 2011. ISBN 3-906980-25-1.