22Rv1
22Rv1 (亦稱CWR-22rv1) 是人類前列腺癌細胞系[1]，最初是分離自嫁接在小鼠體內，並且在其體內繁殖的CWR22R細胞的異種移植物[2][3]。22Rv1細胞對前列腺特異抗原呈現陽性反應，二羥基睪脂酮輕微刺激着細胞的生長，而表皮生長因子則能刺激細胞生長，但是TGFβ-1不能夠抑制細胞增殖[1]。22Rv1細胞產生高滴度的異嗜性鼠白血病相關病毒 (XMRV) [4] 。
參考資料[编辑]
- ^ 1.0 1.1 Sramkoski, RM; Pretlow TG, 2nd; Giaconia, JM; Pretlow, TP; Schwartz, S; Sy, MS; Marengo, SR; Rhim, JS; Zhang, D; Jacobberger, JW. A new human prostate carcinoma cell line, 22Rv1.. In vitro cellular & developmental biology. Animal. NaN, 35 (7): 403–9 [2019-12-17]. PMID 10462204. doi:10.1007/s11626-999-0115-4. （原始内容存档于2019-12-17）.
- ^ Woods-Burnham, L; Basu, A; Cajigas-Du Ross, CK; Love, A; Yates, C; De Leon, M; Roy, S; Casiano, CA. The 22Rv1 prostate cancer cell line carries mixed genetic ancestry: Implications for prostate cancer health disparities research using pre-clinical models.. The Prostate. 2017-12, 77 (16): 1601–1608 [2019-12-17]. PMID 29030865. doi:10.1002/pros.23437.
- ^ Pretlow, TG; Wolman, SR; Micale, MA; Pelley, RJ; Kursh, ED; Resnick, MI; Bodner, DR; Jacobberger, JW; Delmoro, CM; Giaconia, JM. Xenografts of primary human prostatic carcinoma.. Journal of the National Cancer Institute. 1993-03-03, 85 (5): 394–8 [2019-12-17]. PMID 8433392. doi:10.1093/jnci/85.5.394. （原始内容存档于2019-12-17）.
- ^ Yang, J; Battacharya, P; Singhal, R; Kandel, ES. Xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer cells likely represents a laboratory artifact.. Oncotarget. 2011-05, 2 (5): 358–62 [2019-12-17]. PMID 21642749. doi:10.18632/oncotarget.287. （原始内容存档于2019-12-17）.